Detection of five common CFTR mutations by rapid-cycle real-time amplification refractory mutation system PCR.
نویسندگان
چکیده
منابع مشابه
Rapid quantitation of gene therapy specific CFTR expression using the amplification refractory mutation system.
Gene therapy offers the potential of correcting genetic disorders such as cystic fibrosis (CF). By complementing the non-functional endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene with a functional transgene, we anticipate it may alleviate the disease phenotype. All approaches to CF gene therapy rely upon sensitive assays to monitor delivery, expression and maintenanc...
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عنوان ژورنال:
- Clinical chemistry
دوره 50 4 شماره
صفحات -
تاریخ انتشار 2004